Quantification of macular perfusion in healthy children using optical coherence tomography angiography

Abstract Background This study aimed at defining the variance of vessel density (VD) characteristics in macula children with normal eyes. Methods was a cross-sectional which subjects eyes aged 3–18 years were enrolled. The scanned by optical coherence tomography angiography (OCTA). Four age groups as under 7 years, 7–10 11–14 and more than 14 defined. influences age, gender, body mass index on VD analyzed. Results A total 108 from 54 participants mean 10.9 enrolled study. At superficial deep retina capillary plexus (SCP DCP) choriocapillaris (CC), respectively, fovea 20.10%, 36.99%, 75.67%; parafovea, these measurements 53.12%, 55.81%, 69.76%; perifovea, measures 51.38%, 52.46%, 73.47%. median foveal avascular zone (FAZ) 0.30 mm 2 . No significant differences between superior-hemi inferior-hemi found studied plexuses. parafovea perifovea CC differed significantly groups. There no variation macular or sex. FAZ areas different genders. Conclusions difference genders area noted. larger male. Even though this is not longitudinal study, it may provide us hints about vascular development during puberty clinical implications OCTA children.